The Role of PPARs in Disease

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that function as ligand-activated transcription factors. They exist in three isoforms: PPARα, PPARβ/δ, and PPARγ. For all PPARs, lipids are endogenous ligands, linking them directly to metabolism. PPARs form heterodimers with...

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Bibliographic Details
Main Authors: Nicole Wagner, Kay-Dietrich Wagner
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/11/2367