A novel TLE6 mutation, c.541+1G>A, identified using whole‐exome sequencing in a Chinese family with female infertility

A novel TLE6 mutation, c.541+1G>A, identified using whole‐exome sequencing in a Chinese family with female infertility

Abstract Background Oocytes have a lot of maternal RNAs and proteins, which are used by the early embryo before zygotic genome activation. Transducin‐like enhancer of split 6 (TLE6) is a component of a subcortical maternal complex which plays a critical role in early embryonic development. Methods T...

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Bibliographic Details
Main Authors: Bin Mao, Xueling Jia, Hongfang Liu, Xiaojuan Xu, Xiaodong Zhao, Yue Yuan, Hongxing Li, Xiaoling Ma, Lili Zhang
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
female infertility
ICSI
IVF
mutation
TLE6 mutation
Online Access:https://doi.org/10.1002/mgg3.1743

Internet

https://doi.org/10.1002/mgg3.1743

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