Death Receptor Interactions With the Mitochondrial Cell Death Pathway During Immune Cell-, Drug- and Toxin-Induced Liver Damage

Due to its extensive vascularization and physiological function as a filter and storage organ, the liver is constantly exposed to infectious and tumorigenic threat, as well as damaging actions of xenobiotics. Detoxification reactions are essential for the excretion of harmful substances, but harbor...

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Bibliographic Details
Main Authors: Valentina Spinnenhirn, Janine Demgenski, Thomas Brunner
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Bim
JNK
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00072/full