Wisp1 is a circulating factor that stimulates proliferation of adult mouse and human beta cells

Wisp1 is a circulating factor that stimulates proliferation of adult mouse and human beta cells

The proliferation of pancreatic beta cells decreases with age, partly due to systemic changes. Here the authors identify Wisp1 as a circulating factor enriched in young serum that induces adult beta cell proliferation, supporting the idea that young blood factors may be useful to expand beta cell ma...

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Bibliographic Details
Main Authors: Rebeca Fernandez-Ruiz, Ainhoa García-Alamán, Yaiza Esteban, Joan Mir-Coll, Berta Serra-Navarro, Marta Fontcuberta-PiSunyer, Christophe Broca, Mathieu Armanet, Anne Wojtusciszyn, Vardit Kram, Marian F. Young, Josep Vidal, Ramon Gomis, Rosa Gasa
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19657-1

Internet

https://doi.org/10.1038/s41467-020-19657-1

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