Identification of the Common Origins of Osteoclasts, Macrophages, and Dendritic Cells in Human Hematopoiesis

Osteoclasts (OCs) originate from the myeloid cell lineage, but the successive steps in their lineage commitment are ill-defined, especially in humans. To clarify OC origin, we sorted cell populations from pediatric bone marrow (BM) by flow cytometry and assessed their differentiation potential in vi...

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Bibliographic Details
Main Authors: Yanling Xiao, Sebastiaan Zijl, Liqin Wang, Daniel C. de Groot, Maarten J. van Tol, Arjan C. Lankester, Jannie Borst
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115001241