Inhibition of the Fission Machinery Mitigates OPA1 Impairment in Adult Skeletal Muscles

The maintenance of muscle mass and its ability to function relies on a bioenergetic efficient mitochondrial network. This network is highly impacted by fusion and fission events. We have recently shown that the acute deletion of the fusion protein Opa1 induces muscle atrophy, systemic inflammatory r...

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Bibliographic Details
Main Authors: Vanina Romanello, Marco Scalabrin, Mattia Albiero, Bert Blaauw, Luca Scorrano, Marco Sandri
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/6/597