Generation of functional CLL-specific cord blood CTL using CD40-ligated CLL APC.

Generation of functional CLL-specific cord blood CTL using CD40-ligated CLL APC.

Though remissions have been observed following allo-HSCT for the treatment of CLL, many CLL patients are ineligible for transplant due to the lack of HLA-compatible donors. The use of umbilical cord blood (UCB) permits transplantation of many patients who lack HLA-compatible donors due to reduced re...

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Bibliographic Details
Main Authors: William K Decker, Nina Shah, Dongxia Xing, Ruth Lapushin, Sufang Li, Simon N Robinson, Hong Yang, Simrit Parmar, Matthew M Halpert, Michael J Keating, John G Gribben, Jeffrey J Molldrem, Elizabeth J Shpall, William G Wierda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3526610?pdf=render

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http://europepmc.org/articles/PMC3526610?pdf=render

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