An optimized immunohistochemistry technique improves NMO-IgG detection: study comparison with cell-based assays.

An optimized immunohistochemistry technique improves NMO-IgG detection: study comparison with cell-based assays.

Cell-based assays (CBA) have increased the sensitivity of the neuromyelitis optica (NMO)-IgG/aquaporin-4-antibody detection compared to classical tissue-based indirect assays. We describe the sensitivity of an optimized immunohistochemistry (IHC-o) to detect NMO-IgG/aquaporin-4-antibody in compariso...

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Bibliographic Details
Main Authors: Romana Höftberger, Lidia Sabater, Romain Marignier, Fahmy Aboul-Enein, Raphaël Bernard-Valnet, Helmut Rauschka, Anne Ruiz, Yolanda Blanco, Francesc Graus, Josep Dalmau, Albert Saiz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3817095?pdf=render

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http://europepmc.org/articles/PMC3817095?pdf=render

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