A Boolean network control algorithm guided by forward dynamic programming.

Control problem in a biological system is the problem of finding an interventional policy for changing the state of the biological system from an undesirable state, e.g. disease, into a desirable healthy state. Boolean networks are utilized as a mathematical model for gene regulatory networks. This...

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Bibliographic Details
Main Authors: Mohammad Moradi, Sama Goliaei, Mohammad-Hadi Foroughmand-Araabi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0215449