Identification of the active portion of the CCL3 derivative reported to induce antitumor abscopal effect

Background and purpose: Intravenous administration of a single amino acid-substituted chemokine CCL3 derivative named eMIP elicits the abscopal effect (an effect distal to the target), after local irradiation at a tumor-bearing site. To distinguish the active portion of eMIP, we tested the antitumor...

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Bibliographic Details
Main Authors: Tomoko Tsuchiya, Kenshiro Shiraishi, Keiichi Nakagawa, Jae-Ryong Kim, Shiro Kanegasaki
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Clinical and Translational Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S240563081730099X