GspD, The Type II Secretion System Secretin of <i>Leptospira</i>, Protects Hamsters against Lethal Infection with a Virulent <i>L. interrogans</i> Isolate

GspD, The Type II Secretion System Secretin of <i>Leptospira</i>, Protects Hamsters against Lethal Infection with a Virulent <i>L. interrogans</i> Isolate

The wide variety of pathogenic <i>Leptospira</i> serovars and the weak protection offered by the available vaccines encourage the search for protective immunogens against leptospirosis. We found that the secretin GspD of the type II secretion system (T2S) of <i>Leptospira interroga...

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Bibliographic Details
Main Authors: Samantha Paulina Llanos Salinas, Luz Olivia Castillo Sánchez, Giselle Castañeda Miranda, Ernesto Armando Rodríguez Reyes, Liliana Ordoñez López, Rodrigo Mena Bañuelos, Luz Elena Alcaraz Sosa, María Guadalupe Núñez Carrera, Ramírez Ortega José Manuel, Carlos Alfredo Carmona Gasca, James Matsunaga, David A. Haake, Irma Eugenia Candanosa Aranda, Alejandro de la Peña-Moctezuma
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Vaccines
Subjects:
<i>Leptospira</i>
vaccine
recombinant
T2S
GspD
challenge
Online Access:https://www.mdpi.com/2076-393X/8/4/759

Internet

https://www.mdpi.com/2076-393X/8/4/759

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