Arenavirus Induced CCL5 Expression Causes NK Cell-Mediated Melanoma Regression

Arenavirus Induced CCL5 Expression Causes NK Cell-Mediated Melanoma Regression

Immune activation within the tumor microenvironment is one promising approach to induce tumor regression. Certain viruses including oncolytic viruses such as the herpes simplex virus (HSV) and non-oncolytic viruses such as the lymphocytic choriomeningitis virus (LCMV) are potent tools to induce tumo...

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Bibliographic Details
Main Authors: Hilal Bhat, Gregor Zaun, Thamer A. Hamdan, Judith Lang, Tom Adomati, Rosa Schmitz, Sarah-Kim Friedrich, Michael Bergerhausen, Lamin B. Cham, Fanghui Li, Murtaza Ali, Fan Zhou, Vishal Khairnar, Vikas Duhan, Tim Brandenburg, Yara Maria Machlah, Maximilian Schiller, Arshia Berry, Haifeng Xu, Jörg Vollmer, Dieter Häussinger, Beatrice Thier, Aleksandra A. Pandyra, Dirk Schadendorf, Annette Paschen, Martin Schuler, Philipp A. Lang, Karl S. Lang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
arenavirus
virotherapy
immunotherapy
LCMV
innate immunity
CCL5
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01849/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01849/full

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