Effects of peptide on NK cell-mediated MHC I recognition

The inhibitory receptors for MHC class I have a central role in controlling NK cell activity. Soon after their discovery it was found that these receptors have a degree of peptide selectivity. Such peptide selectivity has been demonstrated for all inhibitory KIR tested to date, certain activating K...

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Bibliographic Details
Main Authors: Salim Iqbal Khakoo, Sorcha eCassidy, Kuldeep eCheent
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Immunology
Subjects:
KIR
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00133/full