Estimation of the binding modes with important human cytochrome P450 enzymes, drug interaction potential, pharmacokinetics, and hepatotoxicity of ginger components using molecular docking, computational, and pharmacokinetic modeling studies

Jia-Xuan Qiu,1,2 Zhi-Wei Zhou,3 Zhi-Xu He,4 Xueji Zhang,5 Shu-Feng Zhou,3 Shengrong Zhu11Department of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China; 2Department of Oral and Maxillofacial Surge...

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Bibliographic Details
Main Authors: Qiu JX, Zhou ZW, He ZX, Zhang X, Zhou SF, Zhu S
Format: Article
Language:English
Published: Dove Medical Press 2015-02-01
Series:Drug Design, Development and Therapy
Online Access:http://www.dovepress.com/estimation-of-the-binding-modes-with-important-human-cytochrome-p450-e-peer-reviewed-article-DDDT