Assessment of repeat dose toxicity of Cochleate derived from Neisseria meningitidis proteoliposome in Sprague Dawley rats

The AFCo1 cochleate is a potential novel adjuvant derived from Neisseria meningitidis B proteoliposome. The aim of this study was to assess the safety of AFCo1 by repeated doses in Sprague Dawley rats. Rats were grouped for treatment with AFCo1, placebo formulation or control. Four similar doses of...

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Bibliographic Details
Main Authors: Juan Francisco Infante, Sergio Sifontes, Daniel Francisco Arencibia, Tamara Hernández, Mildrey Fariñas, Oliver Pérez
Format: Article
Language:English
Published: Finlay Ediciones 2012-12-01
Series:VacciMonitor
Subjects:
Online Access:http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1025-028X2012000300001&lng=es&nrm=iso&tlng=en