Klotho/FGF23 and Wnt Signaling as Important Players in the Comorbidities Associated with Chronic Kidney Disease

Fibroblast Growth Factor 23 (FGF23) and Klotho play an essential role in the regulation of mineral metabolism, and both are altered as a consequence of renal failure. FGF23 increases to augment phosphaturia, which prevents phosphate accumulation at the early stages of chronic kidney disease (CKD). T...

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Bibliographic Details
Main Authors: Juan Rafael Muñoz-Castañeda, Cristian Rodelo-Haad, Maria Victoria Pendon-Ruiz de Mier, Alejandro Martin-Malo, Rafael Santamaria, Mariano Rodriguez
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Toxins
Subjects:
ckd
Online Access:https://www.mdpi.com/2072-6651/12/3/185