A bivalent recombinant protein inactivates HIV-1 by targeting the gp41 prehairpin fusion intermediate induced by CD4 D1D2 domains

<p>Abstract</p> <p>Background</p> <p>Most currently approved anti-HIV drugs (<it>e.g.</it>, reverse transcriptase inhibitors, protease inhibitors and fusion/entry inhibitors) must act inside or on surface of the target cell to inhibit HIV infection, but none...

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Bibliographic Details
Main Authors: Lu Lu, Pan Chungen, Li Yuan, Lu Hong, He Wu, Jiang Shibo
Format: Article
Language:English
Published: BMC 2012-12-01
Series:Retrovirology
Subjects:
Online Access:http://www.retrovirology.com/content/9/1/104