A bivalent recombinant protein inactivates HIV-1 by targeting the gp41 prehairpin fusion intermediate induced by CD4 D1D2 domains
<p>Abstract</p> <p>Background</p> <p>Most currently approved anti-HIV drugs (<it>e.g.</it>, reverse transcriptase inhibitors, protease inhibitors and fusion/entry inhibitors) must act inside or on surface of the target cell to inhibit HIV infection, but none...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-12-01
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Series: | Retrovirology |
Subjects: | |
Online Access: | http://www.retrovirology.com/content/9/1/104 |