Optimisation of laboratory methods for whole transcriptomic RNA analyses in human left ventricular biopsies and blood samples of clinical relevance.

Optimisation of laboratory methods for whole transcriptomic RNA analyses in human left ventricular biopsies and blood samples of clinical relevance.

This study aimed to optimise techniques for whole transcriptome and small RNA analyses on clinical tissue samples from patients with cardiovascular disease. Clinical samples often represent a particular challenge to extracting RNA of sufficient quality for robust RNA sequencing analysis, and due to...

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Bibliographic Details
Main Authors: Kerrie L Ford, Maryam Anwar, Rachael Heys, Eltayeb Mohamed Ahmed, Massimo Caputo, Laurence Game, Barnaby C Reeves, Prakash P Punjabi, Gianni D Angelini, Enrico Petretto, Costanza Emanueli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0213685

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https://doi.org/10.1371/journal.pone.0213685

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