RNA‐Binding Protein IGF2BP2/IMP2 is a Critical Maternal Activator in Early Zygotic Genome Activation

RNA‐Binding Protein IGF2BP2/IMP2 is a Critical Maternal Activator in Early Zygotic Genome Activation

Abstract A number of genes involved in zygotic genome activation (ZGA) have been identified, but the RNA‐binding maternal factors that are directly related to ZGA in mice remain unclear. The present study shows that maternal deletion of Igf  2bp2 (also commonly known as Imp2) in mouse embryos causes...

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Bibliographic Details
Main Authors: Hong‐Bin Liu, Tahir Muhammad, Yueshuai Guo, Meng‐Jing Li, Qian‐Qian Sha, Chuan‐Xin Zhang, Hui Liu, Shi‐Gang Zhao, Han Zhao, Hao Zhang, Yan‐Zhi Du, Kang Sun, Kui Liu, Gang Lu, Xue‐Jiang Guo, Jiahao Sha, Heng‐Yu Fan, Fei Gao, Zi‐Jiang Chen
Format: Article
Language:English
Published: Wiley 2019-08-01
Series:Advanced Science
Subjects:
IGF2
IMP2
infertility
RNA‐binding protein
zygotic genome activation
Online Access:https://doi.org/10.1002/advs.201900295

Internet

https://doi.org/10.1002/advs.201900295

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