Dynamic Chromatin Modification Sustains Epithelial-Mesenchymal Transition following Inducible Expression of Snail-1

Dynamic Chromatin Modification Sustains Epithelial-Mesenchymal Transition following Inducible Expression of Snail-1

Epithelial-mesenchymal transition (EMT) is thought to contribute to cancer metastasis, but its underlying mechanisms are not well understood. To define early steps in this cellular transformation, we analyzed human mammary epithelial cells with tightly regulated expression of Snail-1, a master regu...

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Bibliographic Details
Main Authors: Sarah Javaid, Jianmin Zhang, Endre Anderssen, Josh C. Black, Ben S. Wittner, Ken Tajima, David T. Ting, Gromoslaw A. Smolen, Matthew Zubrowski, Rushil Desai, Shyamala Maheswaran, Sridhar Ramaswamy, Johnathan R. Whetstine, Daniel A. Haber
Format: Article
Language:English
Published: Elsevier 2013-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713007183

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