Microfluidic Isolation of Circulating Tumor Cell Clusters by Size and Asymmetry

by Sam H. Au, Jon Edd, Amy E. Stoddard, Keith H. K. Wong, Fabio Fachin, Shyamala Maheswaran, Daniel A. Haber, Shannon L. Stott, Ravi Kapur, Mehmet Toner
Published 2017-05-01

Inhibition of mutant EGFR in lung cancer cells triggers SOX2-FOXO6-dependent survival pathways

by S Michael Rothenberg, Kyle Concannon, Sarah Cullen, Gaylor Boulay, Alexa B Turke, Anthony C Faber, Elizabeth L Lockerman, Miguel N Rivera, Jeffrey A Engelman, Shyamala Maheswaran, Daniel A Haber
Published 2015-02-01

Ultra-fast vitrification of patient-derived circulating tumor cell lines.

by Rebecca D Sandlin, Keith H K Wong, Shannon N Tessier, Anisa Swei, Lauren D Bookstaver, Bennett E Ahearn, Shyamala Maheswaran, Daniel A Haber, Shannon L Stott, Mehmet Toner
Published 2018-01-01

Preservative solution that stabilizes erythrocyte morphology and leukocyte viability under ambient conditions

by Rebecca D. Sandlin, Keith H. K. Wong, Leo Boneschansker, Thomas R. Carey, Kathleen L. Miller, Gregory Rose, Daniel A. Haber, Shyamala Maheswaran, Daniel Irimia, Shannon L. Stott, Mehmet Toner
Published 2017-07-01

Dynamic Chromatin Modification Sustains Epithelial-Mesenchymal Transition following Inducible Expression of Snail-1

by Sarah Javaid, Jianmin Zhang, Endre Anderssen, Josh C. Black, Ben S. Wittner, Ken Tajima, David T. Ting, Gromoslaw A. Smolen, Matthew Zubrowski, Rushil Desai, Shyamala Maheswaran, Sridhar Ramaswamy, Johnathan R. Whetstine, Daniel A. Haber
Published 2013-12-01

Relationship between hepatocellular carcinoma circulating tumor cells and tumor volume

by Rahmi Oklu, Rahul Sheth, Hassan Albadawi, Irun Bhan, A. Fatih Sarioglu, Melissa Choz, Mahnaz Zeinali, Vikram Deshpande, Shyamala Maheswaran, Daniel A. Haber, Shannon L. Stott, Andrew X. Zhu, Lipika Goyal, Mehmet Toner, David T. Ting
Published 2018-07-01

SETD1A protects from senescence through regulation of the mitotic gene expression program

by Ken Tajima, Satoru Matsuda, Toshifumi Yae, Benjamin J. Drapkin, Robert Morris, Myriam Boukhali, Kira Niederhoffer, Valentine Comaills, Taronish Dubash, Linda Nieman, Hongshan Guo, Neelima K. C. Magnus, Nick Dyson, Toshihiro Shioda, Wilhelm Haas, Daniel A. Haber, Shyamala Maheswaran
Published 2019-06-01

HIF1A signaling selectively supports proliferation of breast cancer in the brain

by Richard Y. Ebright, Marcus A. Zachariah, Douglas S. Micalizzi, Ben S. Wittner, Kira L. Niederhoffer, Linda T. Nieman, Brian Chirn, Devon F. Wiley, Benjamin Wesley, Brian Shaw, Edwin Nieblas-Bedolla, Lian Atlas, Annamaria Szabolcs, Anthony J. Iafrate, Mehmet Toner, David T. Ting, Priscilla K. Brastianos, Daniel A. Haber, Shyamala Maheswaran
Published 2020-12-01

Monolithic Chip for High-throughput Blood Cell Depletion to Sort Rare Circulating Tumor Cells

by Fabio Fachin, Philipp Spuhler, Joseph M. Martel-Foley, Jon F. Edd, Thomas A. Barber, John Walsh, Murat Karabacak, Vincent Pai, Melissa Yu, Kyle Smith, Henry Hwang, Jennifer Yang, Sahil Shah, Ruby Yarmush, Lecia V. Sequist, Shannon L. Stott, Shyamala Maheswaran, Daniel A. Haber, Ravi Kapur, Mehmet Toner
Published 2017-09-01

Pancreatic circulating tumor cell profiling identifies LIN28B as a metastasis driver and drug target

by Joseph W. Franses, Julia Philipp, Pavlos Missios, Irun Bhan, Ann Liu, Chittampalli Yashaswini, Eric Tai, Huili Zhu, Matteo Ligorio, Benjamin Nicholson, Elizabeth M. Tassoni, Niyati Desai, Anupriya S. Kulkarni, Annamaria Szabolcs, Theodore S. Hong, Andrew S. Liss, Carlos Fernandez-del Castillo, David P. Ryan, Shyamala Maheswaran, Daniel A. Haber, George Q. Daley, David T. Ting
Published 2020-07-01

Isolation and Molecular Characterization of Circulating Melanoma Cells

by Xi Luo, Devarati Mitra, Ryan J. Sullivan, Ben S. Wittner, Anya M. Kimura, Shiwei Pan, Mai P. Hoang, Brian W. Brannigan, Donald P. Lawrence, Keith T. Flaherty, Lecia V. Sequist, Martin McMahon, Marcus W. Bosenberg, Shannon L. Stott, David T. Ting, Sridhar Ramaswamy, Mehmet Toner, David E. Fisher, Shyamala Maheswaran, Daniel A. Haber
Published 2014-05-01

Whole blood stabilization for the microfluidic isolation and molecular characterization of circulating tumor cells

by Keith H. K. Wong, Shannon N. Tessier, David T. Miyamoto, Kathleen L. Miller, Lauren D. Bookstaver, Thomas R. Carey, Cleo J. Stannard, Vishal Thapar, Eric C. Tai, Kevin D. Vo, Erin S. Emmons, Haley M. Pleskow, Rebecca D. Sandlin, Lecia V. Sequist, David T. Ting, Daniel A. Haber, Shyamala Maheswaran, Shannon L. Stott, Mehmet Toner
Published 2017-11-01

Expression of β-globin by cancer cells promotes cell survival during blood-borne dissemination

by Yu Zheng, David T. Miyamoto, Ben S. Wittner, James P. Sullivan, Nicola Aceto, Nicole Vincent Jordan, Min Yu, Nezihi Murat Karabacak, Valentine Comaills, Robert Morris, Rushil Desai, Niyati Desai, Erin Emmons, John D. Milner, Richard J. Lee, Chin-Lee Wu, Lecia V. Sequist, Wilhelm Haas, David T. Ting, Mehmet Toner, Sridhar Ramaswamy, Shyamala Maheswaran, Daniel A. Haber
Published 2017-02-01

A post-transcriptional program of chemoresistance by AU-rich elements and TTP in quiescent leukemic cells

by Sooncheol Lee, Douglas Micalizzi, Samuel S. Truesdell, Syed I. A. Bukhari, Myriam Boukhali, Jennifer Lombardi-Story, Yasutaka Kato, Min-Kyung Choo, Ipsita Dey-Guha, Fei Ji, Benjamin T. Nicholson, David T. Myers, Dongjun Lee, Maria A. Mazzola, Radhika Raheja, Adam Langenbucher, Nicholas J. Haradhvala, Michael S. Lawrence, Roopali Gandhi, Christopher Tiedje, Manuel D. Diaz-Muñoz, David A. Sweetser, Ruslan Sadreyev, David Sykes, Wilhelm Haas, Daniel A. Haber, Shyamala Maheswaran, Shobha Vasudevan
Published 2020-02-01

Single-Cell RNA Sequencing Identifies Extracellular Matrix Gene Expression by Pancreatic Circulating Tumor Cells

by David T. Ting, Ben S. Wittner, Matteo Ligorio, Nicole Vincent Jordan, Ajay M. Shah, David T. Miyamoto, Nicola Aceto, Francesca Bersani, Brian W. Brannigan, Kristina Xega, Jordan C. Ciciliano, Huili Zhu, Olivia C. MacKenzie, Julie Trautwein, Kshitij S. Arora, Mohammad Shahid, Haley L. Ellis, Na Qu, Nabeel Bardeesy, Miguel N. Rivera, Vikram Deshpande, Cristina R. Ferrone, Ravi Kapur, Sridhar Ramaswamy, Toshi Shioda, Mehmet Toner, Shyamala Maheswaran, Daniel A. Haber
Published 2014-09-01