Mitochondrial and Redox Modifications in Huntington Disease Induced Pluripotent Stem Cells Rescued by CRISPR/Cas9 CAGs Targeting

by Carla Lopes, Carla Lopes, Yang Tang, Yang Tang, Sandra I. Anjo, Sandra I. Anjo, Bruno Manadas, Isabel Onofre, Isabel Onofre, Luís P. de Almeida, Luís P. de Almeida, George Q. Daley, George Q. Daley, George Q. Daley, George Q. Daley, Thorsten M. Schlaeger, Thorsten M. Schlaeger, Ana Cristina Carvalho Rego, Ana Cristina Carvalho Rego
Published 2020-09-01

All-trans retinoic acid directs urothelial specification of murine embryonic stem cells via GATA4/6 signaling mechanisms.

by Joshua R Mauney, Aruna Ramachandran, Richard N Yu, George Q Daley, Rosalyn M Adam, Carlos R Estrada
Published 2010-07-01

microRNA expression during trophectoderm specification.

by Srinivas R Viswanathan, Craig H Mermel, Jun Lu, Chi-Wei Lu, Todd R Golub, George Q Daley
Published 2009-07-01

A robust approach to identifying tissue-specific gene expression regulatory variants using personalized human induced pluripotent stem cells.

by Je-Hyuk Lee, In-Hyun Park, Yuan Gao, Jin Billy Li, Zhe Li, George Q Daley, Kun Zhang, George M Church
Published 2009-11-01

Transplantation of adult mouse iPS cell-derived photoreceptor precursors restores retinal structure and function in degenerative mice.

by Budd A Tucker, In-Hyun Park, Sara D Qi, Henry J Klassen, Caihui Jiang, Jing Yao, Stephen Redenti, George Q Daley, Michael J Young
Published 2011-04-01

Correction: Transplantation of Adult Mouse iPS Cell-Derived Photoreceptor Precursors Restores Retinal Structure and Function in Degenerative Mice.

by Budd A Tucker, In-Hyun Park, Sara D Qi, Henry J Klassen, Caihui Jiang, Jing Yao, Stephen Redenti, George Q Daley, Michael J Young
Published 2015-01-01

The Epithelial-Mesenchymal Transition Factor SNAIL Paradoxically Enhances Reprogramming

by Juli J. Unternaehrer, Rui Zhao, Kitai Kim, Marcella Cesana, John T. Powers, Sutheera Ratanasirintrawoot, Tamer Onder, Tsukasa Shibue, Robert A. Weinberg, George Q. Daley
Published 2014-11-01

Comprehensive Mapping of Pluripotent Stem Cell Metabolism Using Dynamic Genome-Scale Network Modeling

by Sriram Chandrasekaran, Jin Zhang, Zhen Sun, Li Zhang, Christian A. Ross, Yu-Chung Huang, John M. Asara, Hu Li, George Q. Daley, James J. Collins
Published 2017-12-01

Zcchc11 uridylates mature miRNAs to enhance neonatal IGF-1 expression, growth, and survival.

by Matthew R Jones, Matthew T Blahna, Elyse Kozlowski, Kori Y Matsuura, Joseph D Ferrari, Samantha A Morris, John T Powers, George Q Daley, Lee J Quinton, Joseph P Mizgerd
Published 2012-01-01

Reconstruction of complex single-cell trajectories using CellRouter

by Edroaldo Lummertz da Rocha, R. Grant Rowe, Vanessa Lundin, Mohan Malleshaiah, Deepak Kumar Jha, Carlos R. Rambo, Hu Li, Trista E. North, James J. Collins, George Q. Daley
Published 2018-03-01

Engineered Murine HSCs Reconstitute Multi-lineage Hematopoiesis and Adaptive Immunity

by Yi-Fen Lu, Patrick Cahan, Samantha Ross, Julie Sahalie, Patricia M. Sousa, Brandon K. Hadland, Wenqing Cai, Erik Serrao, Alan N. Engelman, Irwin D. Bernstein, George Q. Daley
Published 2016-12-01

Author Correction: Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis

by Alena V. Yermalovich, Jihan K. Osborne, Patricia Sousa, Areum Han, Melissa A. Kinney, Michael J. Chen, Daisy A. Robinton, Helen Montie, Dan S. Pearson, Sean B. Wilson, Alexander N. Combes, Melissa H. Little, George Q. Daley
Published 2020-03-01

Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis

by Alena V. Yermalovich, Jihan K. Osborne, Patricia Sousa, Areum Han, Melissa A. Kinney, Michael J. Chen, Daisy A. Robinton, Helen Montie, Dan S. Pearson, Sean B. Wilson, Alexander N. Combes, Melissa H. Little, George Q. Daley
Published 2019-01-01

Developmental Vitamin D Availability Impacts Hematopoietic Stem Cell Production

by Mauricio Cortes, Michael J. Chen, David L. Stachura, Sarah Y. Liu, Wanda Kwan, Francis Wright, Linda T. Vo, Lindsay N. Theodore, Virginie Esain, Isaura M. Frost, Thorsten M. Schlaeger, Wolfram Goessling, George Q. Daley, Trista E. North
Published 2016-10-01

Therapeutic Potential of Human Induced Pluripotent Stem Cells in Experimental Stroke

by Da-Jeong Chang, Nayeon Lee, In-Hyun Park, Chunggab Choi, Iksoo Jeon, Jihye Kwon, Seung-Hun Oh, Dong Ah Shin, Jeong Tae Do, Dong Ryul Lee, Hyunseung Lee, Kwan Soo Hong, George Q. Daley, Jihwan Song D.Phil., Hyeyoung Moon
Published 2013-08-01

Pancreatic circulating tumor cell profiling identifies LIN28B as a metastasis driver and drug target

by Joseph W. Franses, Julia Philipp, Pavlos Missios, Irun Bhan, Ann Liu, Chittampalli Yashaswini, Eric Tai, Huili Zhu, Matteo Ligorio, Benjamin Nicholson, Elizabeth M. Tassoni, Niyati Desai, Anupriya S. Kulkarni, Annamaria Szabolcs, Theodore S. Hong, Andrew S. Liss, Carlos Fernandez-del Castillo, David P. Ryan, Shyamala Maheswaran, Daniel A. Haber, George Q. Daley, David T. Ting
Published 2020-07-01

Precise let-7 expression levels balance organ regeneration against tumor suppression

by Linwei Wu, Liem H Nguyen, Kejin Zhou, T Yvanka de Soysa, Lin Li, Jason B Miller, Jianmin Tian, Joseph Locker, Shuyuan Zhang, Gen Shinoda, Marc T Seligson, Lauren R Zeitels, Asha Acharya, Sam C Wang, Joshua T Mendell, Xiaoshun He, Jinsuke Nishino, Sean J Morrison, Daniel J Siegwart, George Q Daley, Ng Shyh-Chang, Hao Zhu
Published 2015-10-01

RNAi Reveals Phase-Specific Global Regulators of Human Somatic Cell Reprogramming

by Cheng-Xu Delon Toh, Jun-Wei Chan, Zheng-Shan Chong, Hao Fei Wang, Hong Chao Guo, Sandeep Satapathy, Dongrui Ma, Germaine Yen Lin Goh, Ekta Khattar, Lin Yang, Vinay Tergaonkar, Young-Tae Chang, James J. Collins, George Q. Daley, Keng Boon Wee, Chadi A. EL Farran, Hu Li, Yoon-Pin Lim, Frederic A. Bard, Yuin-Han Loh
Published 2016-06-01

PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells

by Partha Pratim Das, David A. Hendrix, Effie Apostolou, Alice H. Buchner, Matthew C. Canver, Semir Beyaz, Damir Ljuboja, Rachael Kuintzle, Woojin Kim, Rahul Karnik, Zhen Shao, Huafeng Xie, Jian Xu, Alejandro De Los Angeles, Yingying Zhang, Junho Choe, Don Leong Jia Jun, Xiaohua Shen, Richard I. Gregory, George Q. Daley, Alexander Meissner, Manolis Kellis, Konrad Hochedlinger, Jonghwan Kim, Stuart H. Orkin
Published 2015-09-01

Setting Global Standards for Stem Cell Research and Clinical Translation: The 2016 ISSCR Guidelines

by George Q. Daley, Insoo Hyun, Jane F. Apperley, Roger A. Barker, Nissim Benvenisty, Annelien L. Bredenoord, Christopher K. Breuer, Timothy Caulfield, Marcelle I. Cedars, Joyce Frey-Vasconcells, Helen E. Heslop, Ying Jin, Richard T. Lee, Christopher McCabe, Megan Munsie, Charles E. Murry, Steven Piantadosi, Mahendra Rao, Heather M. Rooke, Douglas Sipp, Lorenz Studer, Jeremy Sugarman, Masayo Takahashi, Mark Zimmerman, Jonathan Kimmelman
Published 2016-06-01