In Vivo and In Vitro Dynamics of Undifferentiated Embryonic Cell Transcription Factor 1

by Christina Galonska, Zachary D. Smith, Alexander Meissner
Published 2014-03-01

A model for genetic and epigenetic regulatory networks identifies rare pathways for transcription factor induced pluripotency.

by Maxim N Artyomov, Alexander Meissner, Arup K Chakraborty
Published 2010-05-01

Differential regulation of OCT4 targets facilitates reacquisition of pluripotency

by Sudhir Thakurela, Camille Sindhu, Evgeny Yurkovsky, Christina Riemenschneider, Zachary D. Smith, Iftach Nachman, Alexander Meissner
Published 2019-09-01

In vivo Firre and Dxz4 deletion elucidates roles for autosomal gene regulation

by Daniel Andergassen, Zachary D Smith, Jordan P Lewandowski, Chiara Gerhardinger, Alexander Meissner, John L Rinn
Published 2019-11-01

Topological isolation of developmental regulators in mammalian genomes

by Hua-Jun Wu, Alexandro Landshammer, Elena K. Stamenova, Adriano Bolondi, Helene Kretzmer, Alexander Meissner, Franziska Michor
Published 2021-08-01

Probabilistic Modeling of Reprogramming to Induced Pluripotent Stem Cells

by Lin L. Liu, Justin Brumbaugh, Ori Bar-Nur, Zachary Smith, Matthias Stadtfeld, Alexander Meissner, Konrad Hochedlinger, Franziska Michor
Published 2016-12-01

Zika Virus Alters DNA Methylation of Neural Genes in an Organoid Model of the Developing Human Brain

by Sylvie Janssens, Michael Schotsaert, Rahul Karnik, Vinod Balasubramaniam, Marion Dejosez, Alexander Meissner, Adolfo García-Sastre, Thomas P. Zwaka, Jack A. Gilbert
Published 2018-02-01

Identification of distinct loci for de novo DNA methylation by DNMT3A and DNMT3B during mammalian development

by Masaki Yagi, Mio Kabata, Akito Tanaka, Tomoyo Ukai, Sho Ohta, Kazuhiko Nakabayashi, Masahito Shimizu, Kenichiro Hata, Alexander Meissner, Takuya Yamamoto, Yasuhiro Yamada
Published 2020-06-01

In vivo control of CpG and non-CpG DNA methylation by DNA methyltransferases.

by Julia Arand, David Spieler, Tommy Karius, Miguel R Branco, Daniela Meilinger, Alexander Meissner, Thomas Jenuwein, Guoliang Xu, Heinrich Leonhardt, Verena Wolf, Jörn Walter
Published 2012-06-01

X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs

by Vincent Pasque, Rahul Karnik, Constantinos Chronis, Paula Petrella, Justin Langerman, Giancarlo Bonora, Juan Song, Lotte Vanheer, Anupama Sadhu Dimashkie, Alexander Meissner, Kathrin Plath
Published 2018-05-01

Genomic distribution and inter-sample variation of non-CpG methylation across human cell types.

by Michael J Ziller, Fabian Müller, Jing Liao, Yingying Zhang, Hongcang Gu, Christoph Bock, Patrick Boyle, Charles B Epstein, Bradley E Bernstein, Thomas Lengauer, Andreas Gnirke, Alexander Meissner
Published 2011-12-01

Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors

by Marie E Jönsson, Per Ludvik Brattås, Charlotte Gustafsson, Rebecca Petri, David Yudovich, Karolina Pircs, Shana Verschuere, Sofia Madsen, Jenny Hansson, Jonas Larsson, Robert Månsson, Alexander Meissner, Johan Jakobsson
Published 2019-07-01

Targets and genomic constraints of ectopic Dnmt3b expression

by Yingying Zhang, Jocelyn Charlton, Rahul Karnik, Isabel Beerman, Zachary D Smith, Hongcang Gu, Patrick Boyle, Xiaoli Mi, Kendell Clement, Ramona Pop, Andreas Gnirke, Derrick J Rossi, Alexander Meissner
Published 2018-11-01

Information recovery from low coverage whole-genome bisulfite sequencing

by Emanuele Libertini, Simon C. Heath, Rifat A. Hamoudi, Marta Gut, Michael J. Ziller, Agata Czyz, Victor Ruotti, Hendrik G. Stunnenberg, Mattia Frontini, Willem H. Ouwehand, Alexander Meissner, Ivo G. Gut, Stephan Beck
Published 2016-06-01

Age- and Pregnancy-Associated DNA Methylation Changes in Mammary Epithelial Cells

by Sung Jin Huh, Kendell Clement, David Jee, Alessandra Merlini, Sibgat Choudhury, Reo Maruyama, Ronnie Yoo, Anna Chytil, Patrick Boyle, Fei Ann Ran, Harold L. Moses, Mary Helen Barcellos-Hoff, Laurie Jackson-Grusby, Alexander Meissner, Kornelia Polyak
Published 2015-02-01

Genome-wide tracking of dCas9-methyltransferase footprints

by Christina Galonska, Jocelyn Charlton, Alexandra L. Mattei, Julie Donaghey, Kendell Clement, Hongcang Gu, Arman W. Mohammad, Elena K. Stamenova, Davide Cacchiarelli, Sven Klages, Bernd Timmermann, Tobias Cantz, Hans R. Schöler, Andreas Gnirke, Michael J. Ziller, Alexander Meissner
Published 2018-02-01

Transcriptional and Chromatin Dynamics of Muscle Regeneration after Severe Trauma

by Carlos A. Aguilar, Ramona Pop, Anna Shcherbina, Alain Watts, Ronald W. Matheny Jr., Davide Cacchiarelli, Woojin M. Han, Eunjung Shin, Shadi A. Nakhai, Young C. Jang, Christopher T. Carrigan, Casey A. Gifford, Melissa A. Kottke, Marcella Cesana, Jackson Lee, Maria L. Urso, Alexander Meissner
Published 2016-11-01

Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL

by Alessandro Pastore, Federico Gaiti, Sydney X. Lu, Ryan M. Brand, Scott Kulm, Ronan Chaligne, Hongcang Gu, Kevin Y. Huang, Elena K. Stamenova, Wendy Béguelin, Yanwen Jiang, Rafael C. Schulman, Kyu-Tae Kim, Alicia Alonso, John N. Allan, Richard R. Furman, Andreas Gnirke, Catherine J. Wu, Ari M. Melnick, Alexander Meissner, Bradley E. Bernstein, Omar Abdel-Wahab, Dan A. Landau
Published 2019-04-01

PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells

by Partha Pratim Das, David A. Hendrix, Effie Apostolou, Alice H. Buchner, Matthew C. Canver, Semir Beyaz, Damir Ljuboja, Rachael Kuintzle, Woojin Kim, Rahul Karnik, Zhen Shao, Huafeng Xie, Jian Xu, Alejandro De Los Angeles, Yingying Zhang, Junho Choe, Don Leong Jia Jun, Xiaohua Shen, Richard I. Gregory, George Q. Daley, Alexander Meissner, Manolis Kellis, Konrad Hochedlinger, Jonghwan Kim, Stuart H. Orkin
Published 2015-09-01

Differential DNA methylation of vocal and facial anatomy genes in modern humans

by David Gokhman, Malka Nissim-Rafinia, Lily Agranat-Tamir, Genevieve Housman, Raquel García-Pérez, Esther Lizano, Olivia Cheronet, Swapan Mallick, Maria A. Nieves-Colón, Heng Li, Songül Alpaslan-Roodenberg, Mario Novak, Hongcang Gu, Jason M. Osinski, Manuel Ferrando-Bernal, Pere Gelabert, Iddi Lipende, Deus Mjungu, Ivanela Kondova, Ronald Bontrop, Ottmar Kullmer, Gerhard Weber, Tal Shahar, Mona Dvir-Ginzberg, Marina Faerman, Ellen E. Quillen, Alexander Meissner, Yonatan Lahav, Leonid Kandel, Meir Liebergall, María E. Prada, Julio M. Vidal, Richard M. Gronostajski, Anne C. Stone, Benjamin Yakir, Carles Lalueza-Fox, Ron Pinhasi, David Reich, Tomas Marques-Bonet, Eran Meshorer, Liran Carmel
Published 2020-03-01