Comparison of methods for competitive tests of pathway analysis.

by Marina Evangelou, Augusto Rendon, Willem H Ouwehand, Lorenz Wernisch, Frank Dudbridge
Published 2012-01-01

A loss of function screen of identified genome-wide association study Loci reveals new genes controlling hematopoiesis.

by Ewa Bielczyk-Maczyńska, Jovana Serbanovic-Canic, Lauren Ferreira, Nicole Soranzo, Derek L Stemple, Willem H Ouwehand, Ana Cvejic
Published 2014-07-01

Single nucleotide polymorphisms with cis-regulatory effects on long non-coding transcripts in human primary monocytes.

by Jonas Carlsson Almlöf, Per Lundmark, Anders Lundmark, Bing Ge, Tomi Pastinen, Cardiogenics Consortium, Alison H Goodall, François Cambien, Panos Deloukas, Willem H Ouwehand, Ann-Christine Syvänen
Published 2014-01-01

Information recovery from low coverage whole-genome bisulfite sequencing

by Emanuele Libertini, Simon C. Heath, Rifat A. Hamoudi, Marta Gut, Michael J. Ziller, Agata Czyz, Victor Ruotti, Hendrik G. Stunnenberg, Mattia Frontini, Willem H. Ouwehand, Alexander Meissner, Ivo G. Gut, Stephan Beck
Published 2016-06-01

The influence of rare variants in circulating metabolic biomarkers.

by Fernando Riveros-Mckay, Clare Oliver-Williams, Savita Karthikeyan, Klaudia Walter, Kousik Kundu, Willem H Ouwehand, David Roberts, Emanuele Di Angelantonio, Nicole Soranzo, John Danesh, INTERVAL Study, Eleanor Wheeler, Eleftheria Zeggini, Adam S Butterworth, Inês Barroso
Published 2020-03-01

Single nucleotide variants in the protein C pathway and mortality in dialysis patients.

by Gürbey Ocak, Christiane Drechsler, Carla Y Vossen, Hans L Vos, Frits R Rosendaal, Pieter H Reitsma, Michael M Hoffmann, Winfried März, Willem H Ouwehand, Raymond T Krediet, Elisabeth W Boeschoten, Friedo W Dekker, Christoph Wanner, Marion Verduijn
Published 2014-01-01

Correction: Maps of Open Chromatin Guide the Functional Follow-Up of Genome-Wide Association Signals: Application to Hematological Traits.

by Dirk S. Paul, James P. Nisbet, Tsun-Po Yang, Stuart Meacham, Augusto Rendon, Katta Hautaviita, Jonna Tallila, Jacqui White, Marloes R. Tijssen, Suthesh Sivapalaratnam, Hanneke Basart, Mieke D. Trip, Berthold Göttgens, Nicole Soranzo, Willem H. Ouwehand, Panos Deloukas
Published 2011-07-01

SNP in human ARHGEF3 promoter is associated with DNase hypersensitivity, transcript level and platelet function, and Arhgef3 KO mice have increased mean platelet volume.

by Siying Zou, Alexandra M Teixeira, Myrto Kostadima, William J Astle, Aparna Radhakrishnan, Lukas Mikolaj Simon, Lucy Truman, Jennifer S Fang, John Hwa, Ping-Xia Zhang, Pim van der Harst, Paul F Bray, Willem H Ouwehand, Mattia Frontini, Diane S Krause
Published 2017-01-01

Monocyte gene expression signature of patients with early onset coronary artery disease.

by Suthesh Sivapalaratnam, Hanneke Basart, Nicholas A Watkins, Stepanie Maiwald, Augusto Rendon, Unni Krishnan, Brigitte M Sondermeijer, Esther E Creemers, Sara J Pinto-Sietsma, Kees Hovingh, Willem H Ouwehand, John J P Kastelein, Alison H Goodall, Mieke D Trip
Published 2012-01-01

Complex exon-intron marking by histone modifications is not determined solely by nucleosome distribution.

by Pawandeep Dhami, Peter Saffrey, Alexander W Bruce, Shane C Dillon, Kelly Chiang, Nicolas Bonhoure, Christoph M Koch, Jackie Bye, Keith James, Nicola S Foad, Peter Ellis, Nicholas A Watkins, Willem H Ouwehand, Cordelia Langford, Robert M Andrews, Ian Dunham, David Vetrie
Published 2010-08-01

An experimentally validated network of nine haematopoietic transcription factors reveals mechanisms of cell state stability

by Judith Schütte, Huange Wang, Stella Antoniou, Andrew Jarratt, Nicola K Wilson, Joey Riepsaame, Fernando J Calero-Nieto, Victoria Moignard, Silvia Basilico, Sarah J Kinston, Rebecca L Hannah, Mun Chiang Chan, Sylvia T Nürnberg, Willem H Ouwehand, Nicola Bonzanni, Marella FTR de Bruijn, Berthold Göttgens
Published 2016-02-01

Correction: Maps of Open Chromatin Guide the Functional Follow-Up of Genome-Wide Association Signals: Application to Hematological Traits

by Dirk S. Paul, James P. Nisbet, Tsun-Po Yang, Stuart Meacham, Augusto Rendon, Katta Hautaviita, Jonna Tallila, Jacqui White, Marloes R. Tijssen, Suthesh Sivapalaratnam, Hanneke Basart, Mieke D. Trip, Consortium Cardiogenics, Consortium MuTHER, Berthold Göttgens, Nicole Soranzo, Willem H. Ouwehand, Panos Deloukas
Published 2011-07-01

Correction: Comprehensive Exploration of the Effects of miRNA SNPs on Monocyte Gene Expression.

by Nicolas Greliche, Tanja Zeller, Philipp S. Wild, Maxime Rotival, Arne Schillert, Andreas Ziegler, Panos Deloukas, Jeanette Erdmann, Christian Hengstenberg, Willem H. Ouwehand, Nilesh J. Samani, Heribert Schunkert, Thomas Munzel, Karl J. Lackner, François Cambien, Alison H. Goodall, Laurence Tiret, Stefan Blankenberg, David-Alexandre Trégouët
Published 2012-01-01

Maps of open chromatin guide the functional follow-up of genome-wide association signals: application to hematological traits.

by Dirk S Paul, James P Nisbet, Tsun-Po Yang, Stuart Meacham, Augusto Rendon, Katta Hautaviita, Jonna Tallila, Jacqui White, Marloes R Tijssen, Suthesh Sivapalaratnam, Hanneke Basart, Mieke D Trip, Cardiogenics Consortium, MuTHER Consortium, Berthold Göttgens, Nicole Soranzo, Willem H Ouwehand, Panos Deloukas
Published 2011-06-01

Correction: Comprehensive Exploration of the Effects of miRNA SNPs on Monocyte Gene Expression

by Nicolas Greliche, Tanja Zeller, Philipp S. Wild, Maxime Rotival, Arne Schillert, Andreas Ziegler, Cardiogenics Consortium, Panos Deloukas, Jeanette Erdmann, Christian Hengstenberg, Willem H. Ouwehand, Nilesh J. Samani, Heribert Schunkert, Thomas Munzel, Karl J. Lackner, François Cambien, Alison H. Goodall, Laurence Tiret, Stefan Blankenberg, David-Alexandre Trégouët
Published 2012-01-01

Comprehensive exploration of the effects of miRNA SNPs on monocyte gene expression.

by Nicolas Greliche, Tanja Zeller, Philipp S Wild, Maxime Rotival, Arne Schillert, Andreas Ziegler, Cardiogenics Consortium, Panos Deloukas, Jeanette Erdmann, Christian Hengstenberg, Willem H Ouwehand, Nilesh J Samani, Heribert Schunkert, Thomas Munzel, Karl J Lackner, François Cambien, Alison H Goodall, Laurence Tiret, Stefan Blankenberg, David-Alexandre Trégouët
Published 2012-01-01

Genome-wide haplotype analysis of cis expression quantitative trait loci in monocytes.

by Sophie Garnier, Vinh Truong, Jessy Brocheton, Tanja Zeller, Maxime Rovital, Philipp S Wild, Andreas Ziegler, Cardiogenics Consortium, Thomas Munzel, Laurence Tiret, Stefan Blankenberg, Panos Deloukas, Jeannette Erdmann, Christian Hengstenberg, Nilesh J Samani, Heribert Schunkert, Willem H Ouwehand, Alison H Goodall, François Cambien, David-Alexandre Trégouët
Published 2013-01-01

Complex structural variants in Mendelian disorders: identification and breakpoint resolution using short- and long-read genome sequencing

by Alba Sanchis-Juan, Jonathan Stephens, Courtney E. French, Nicholas Gleadall, Karyn Mégy, Christopher Penkett, Olga Shamardina, Kathleen Stirrups, Isabelle Delon, Eleanor Dewhurst, Helen Dolling, Marie Erwood, Detelina Grozeva, Luca Stefanucci, Gavin Arno, Andrew R. Webster, Trevor Cole, Topun Austin, Ricardo Garcia Branco, Willem H. Ouwehand, F. Lucy Raymond, Keren J. Carss
Published 2018-12-01

Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming

by Thomas Moreau, Amanda L. Evans, Louella Vasquez, Marloes R. Tijssen, Ying Yan, Matthew W. Trotter, Daniel Howard, Maria Colzani, Meera Arumugam, Wing Han Wu, Amanda Dalby, Riina Lampela, Guenaelle Bouet, Catherine M. Hobbs, Dean C. Pask, Holly Payne, Tatyana Ponomaryov, Alexander Brill, Nicole Soranzo, Willem H. Ouwehand, Roger A. Pedersen, Cedric Ghevaert
Published 2016-04-01

Correction: Corrigendum: Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming

by Thomas Moreau, Amanda L. Evans, Louella Vasquez, Marloes R. Tijssen, Ying Yan, Matthew W. Trotter, Daniel Howard, Maria Colzani, Meera Arumugam, Wing Han Wu, Amanda Dalby, Riina Lampela, Guenaelle Bouet, Catherine M. Hobbs, Dean C. Pask, Holly Payne, Tatyana Ponomaryov, Alexander Brill, Nicole Soranzo, Willem H. Ouwehand, Roger A. Pedersen, Cedric Ghevaert
Published 2017-07-01