Tissue Specific Sensitivity of Mitochondrial Permeability Transition Pore to Ca2+ Ions

Tissue Specific Sensitivity of Mitochondrial Permeability Transition Pore to Ca2+ Ions

Ca2+-induced opening of the mitochondrial permeability transition pore (MPTP) is involved in induction of apoptotic and necrotic processes. We studied sensitivity of MPTP to calcium using the model of Ca2+-induced, cyclosporine A-sensitive mitochondrial swelling. Presented data indicate that the ext...

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Bibliographic Details
Main Authors: René Endlicher, Pavla Křiváková, Halka Lotková, Marie Milerová, Zdeněk Drahota, Zuzana Červinková
Format: Article
Language:English
Published: Karolinum Press 2009-01-01
Series:Acta Medica
Subjects:
Mitochondria
MPTP
Swelling
Cell death
Apoptosis
Necrosis
Online Access:https://actamedica.lfhk.cuni.cz/52/2/0069/

Internet

https://actamedica.lfhk.cuni.cz/52/2/0069/

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