Reproductive period and epigenetic modifications of the oxidative phosphorylation pathway in the human prefrontal cortex.

PURPOSE:Human females have a unique duration of post-reproductive longevity, during which sex-specific mechanisms ma influence later-life mechanisms of neuronal resilience and vulnerability. The maintenance of energy metabolism, through the oxidative phosphorylation (OXPHOS) apparatus, is essential...

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Bibliographic Details
Main Authors: Riley M Bove, Ellis Patrick, Cristin McCabe Aubin, Gyan Srivastava, Julie A Schneider, David A Bennett, Philip L De Jager, Lori B Chibnik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6063396?pdf=render