Vaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin

Vaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin

Abstract Background Preterm prelabour rupture of the fetal membranes (PPROM) precedes 30% of preterm births and is a risk factor for early onset neonatal sepsis. As PPROM is strongly associated with ascending vaginal infection, prophylactic antibiotics are widely used. The evolution of vaginal micro...

Full description

Bibliographic Details
Main Authors: Richard G. Brown, Julian R. Marchesi, Yun S. Lee, Ann Smith, Benjamin Lehne, Lindsay M. Kindinger, Vasso Terzidou, Elaine Holmes, Jeremy K. Nicholson, Phillip R. Bennett, David A. MacIntyre
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Medicine
Subjects:
Vaginal microbiota
Preterm birth
Preterm prelabour rupture of membranes
Antibiotics
Erythromycin
Neonatal sepsis
Online Access:http://link.springer.com/article/10.1186/s12916-017-0999-x

Internet

http://link.springer.com/article/10.1186/s12916-017-0999-x

Similar Items