Regulation of sonic hedgehog-<it>GLI1 </it>downstream target genes <it>PTCH1, Cyclin D2, Plakoglobin, PAX6 and NKX2.2 </it>and their epigenetic status in medulloblastoma and astrocytoma
<p>Abstract</p> <p>Background</p> <p>The Sonic hedgehog (Shh) signaling pathway is critical for cell growth and differentiation. Impairment of this pathway can result in both birth defects and cancer. Despite its importance in cancer development, the Shh pathway has not...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-11-01
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| Series: | BMC Cancer |
| Online Access: | http://www.biomedcentral.com/1471-2407/10/614 |