Genetic Polymorphisms Affecting IDO1 or IDO2 Activity Differently Associate With Aspergillosis in Humans

Genetic Polymorphisms Affecting IDO1 or IDO2 Activity Differently Associate With Aspergillosis in Humans

Aspergillus is the causative agent of human diseases ranging from asthma to invasive infection. Genetic and environmental factors are crucial in regulating the interaction between the host and Aspergillus. The role played by the enzyme indoleamine 2,3-dioxygenase 1 (IDO1), which catalyzes the first...

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Bibliographic Details
Main Authors: Valerio Napolioni, Marilena Pariano, Monica Borghi, Vasilis Oikonomou, Claudia Galosi, Antonella De Luca, Claudia Stincardini, Carmine Vacca, Giorgia Renga, Vincenzina Lucidi, Carla Colombo, Ersilia Fiscarelli, Cornelia Lass-Flörl, Alessandra Carotti, Lucia D'Amico, Fabio Majo, Maria Chiara Russo, Helmut Ellemunter, Angelica Spolzino, Paolo Mosci, Stefano Brancorsini, Franco Aversa, Andrea Velardi, Luigina Romani, Claudio Costantini
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
IDO1
IDO2
aspergillosis
cystic fibrosis
hematopoietic stem cell transplantation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00890/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00890/full

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