Next-Generation Genome-Scale Metabolic Modeling through Integration of Regulatory Mechanisms

Genome-scale metabolic models (GEMs) are powerful tools for understanding metabolism from a systems-level perspective. However, GEMs in their most basic form fail to account for cellular regulation. A diverse set of mechanisms regulate cellular metabolism, enabling organisms to respond to a wide ran...

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Bibliographic Details
Main Authors: Carolina H. Chung, Da-Wei Lin, Alec Eames, Sriram Chandrasekaran
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/11/9/606