Next-Generation Genome-Scale Metabolic Modeling through Integration of Regulatory Mechanisms
Genome-scale metabolic models (GEMs) are powerful tools for understanding metabolism from a systems-level perspective. However, GEMs in their most basic form fail to account for cellular regulation. A diverse set of mechanisms regulate cellular metabolism, enabling organisms to respond to a wide ran...
Main Authors: | Carolina H. Chung, Da-Wei Lin, Alec Eames, Sriram Chandrasekaran |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-09-01
|
Series: | Metabolites |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-1989/11/9/606 |
Similar Items
-
Genome-scale network model of metabolism and histone acetylation reveals metabolic dependencies of histone deacetylase inhibitors
by: Fangzhou Shen, et al.
Published: (2019-03-01) -
Automated generation of genome-scale metabolic draft reconstructions based on KEGG
by: Emil Karlsen, et al.
Published: (2018-12-01) -
Bayesian Integrative Modeling of Genome-Scale Metabolic and Regulatory Networks
by: Hanen Mhamdi, et al.
Published: (2020-01-01) -
Genome Scale Modeling to Study the Metabolic Competition between Cells in the Tumor Microenvironment
by: Itziar Frades, et al.
Published: (2021-09-01) -
A Protocol for Generating and Exchanging (Genome-Scale) Metabolic Resource Allocation Models
by: Alexandra-M. Reimers, et al.
Published: (2017-09-01)