Reduced functional reserve in patients with age-related white matter changes: a preliminary FMRI study of working memory.

Subcortical age-related white matter changes (ARWMC) are a frequent finding in healthy elderly people suggested to cause secondary tissue changes and possibly affecting cognitive processes. We aimed to determine the influence of the extent of ARWMC load on attention and working memory processes in h...

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Bibliographic Details
Main Authors: Martin Griebe, Michael Amann, Jochen G Hirsch, Lutz Achtnichts, Michael G Hennerici, Achim Gass, Kristina Szabo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4131876?pdf=render