Pharmacokinetic evaluation of a 1,3-dicyclohexylurea nanosuspension formulation to support early efficacy assessment

Pharmacokinetic evaluation of a 1,3-dicyclohexylurea nanosuspension formulation to support early efficacy assessment

<p>Abstract</p><p>Time and resource constraints necessitate increasingly early decisions to advance or halt pre-clinical drug discovery programs. Early discovery or &#8220;tool&#8221; compounds may be potent inhibitors of new targets, but all too often they exhibit poor pha...

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Bibliographic Details
Main Authors: Chiang Po-Chang, Ghosh Sarbani, Roberds Steven, Wahlstrom Jan, Warren Chad, Wene Steve, Albin Lesley, Smith Mark
Format: Article
Language:English
Published: SpringerOpen 2007-01-01
Series:Nanoscale Research Letters
Subjects:
Nanosuspension
Formulation
Pharmacokinetics
Efficacy
Tool compounds
Online Access:http://dx.doi.org/10.1007/s11671-007-9063-7

Internet

http://dx.doi.org/10.1007/s11671-007-9063-7

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