ChIP-Seq and RNA-Seq reveal an AmrZ-mediated mechanism for cyclic di-GMP synthesis and biofilm development by Pseudomonas aeruginosa.

ChIP-Seq and RNA-Seq reveal an AmrZ-mediated mechanism for cyclic di-GMP synthesis and biofilm development by Pseudomonas aeruginosa.

The transcription factor AmrZ regulates genes important for P. aeruginosa virulence, including type IV pili, extracellular polysaccharides, and the flagellum; however, the global effect of AmrZ on gene expression remains unknown, and therefore, AmrZ may directly regulate many additional genes that a...

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Bibliographic Details
Main Authors: Christopher J Jones, David Newsom, Benjamin Kelly, Yasuhiko Irie, Laura K Jennings, Binjie Xu, Dominique H Limoli, Joe J Harrison, Matthew R Parsek, Peter White, Daniel J Wozniak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3946381?pdf=render

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http://europepmc.org/articles/PMC3946381?pdf=render

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