The capping domain in RalF regulates effector functions.

The capping domain in RalF regulates effector functions.

The Legionella pneumophila effector protein RalF functions as a guanine nucleotide exchange factor (GEF) that activates the host small GTPase protein ADP-ribosylation factor (Arf), and recruits this host protein to the vacuoles in which this pathogen resides. GEF activity is conferred by the Sec7 do...

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Bibliographic Details
Main Authors: Eric Alix, Laurent Chesnel, Brad J Bowzard, Aimee M Tucker, Anna Delprato, Jacqueline Cherfils, David O Wood, Richard A Kahn, Craig R Roy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3499574?pdf=render

Internet

http://europepmc.org/articles/PMC3499574?pdf=render

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