Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1.

Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1.

Restless legs syndrome (RLS) is a sensorimotor disorder with an age-dependent prevalence of up to 10% in the general population above 65 years of age. Affected individuals suffer from uncomfortable sensations and an urge to move in the lower limbs that occurs mainly in resting situations during the...

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Main Authors: Juliane Winkelmann, Darina Czamara, Barbara Schormair, Franziska Knauf, Eva C Schulte, Claudia Trenkwalder, Yves Dauvilliers, Olli Polo, Birgit Högl, Klaus Berger, Andrea Fuhs, Nadine Gross, Karin Stiasny-Kolster, Wolfgang Oertel, Cornelius G Bachmann, Walter Paulus, Lan Xiong, Jacques Montplaisir, Guy A Rouleau, Ingo Fietze, Jana Vávrová, David Kemlink, Karel Sonka, Sona Nevsimalova, Siong-Chi Lin, Zbigniew Wszolek, Carles Vilariño-Güell, Matthew J Farrer, Viola Gschliesser, Birgit Frauscher, Tina Falkenstetter, Werner Poewe, Richard P Allen, Christopher J Earley, William G Ondo, Wei-Dong Le, Derek Spieler, Maria Kaffe, Alexander Zimprich, Johannes Kettunen, Markus Perola, Kaisa Silander, Isabelle Cournu-Rebeix, Marcella Francavilla, Claire Fontenille, Bertrand Fontaine, Pavel Vodicka, Holger Prokisch, Peter Lichtner, Paul Peppard, Juliette Faraco, Emmanuel Mignot, Christian Gieger, Thomas Illig, H-Erich Wichmann, Bertram Müller-Myhsok, Thomas Meitinger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-07-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3136436?pdf=render

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http://europepmc.org/articles/PMC3136436?pdf=render

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