Glutamate receptor expression and chronic glutamate toxicity in rat motor cortex

In addition to the loss of spinal motor neurons, amyotrophic lateral sclerosis (ALS) is also associated with degeneration of corticospinal layer V pyramidal neurons and decreased glutamate transport in the cortex. We characterized the glutamate receptors on corticospinal neurons in acutely isolated...

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Bibliographic Details
Main Authors: Kate C. Young, Daniel S. McGehee, James R. Brorson
Format: Article
Language:English
Published: Elsevier 2007-04-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106003111