Multi-compartment T2 relaxometry using a spatially constrained multi-Gaussian model.

The brain's myelin content can be mapped by T2-relaxometry, which resolves multiple differentially relaxing T2 pools from multi-echo MRI. Unfortunately, the conventional fitting procedure is a hard and numerically ill-posed problem. Consequently, the T2 distributions and myelin maps become very...

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Bibliographic Details
Main Authors: Ashish Raj, Sneha Pandya, Xiaobo Shen, Eve LoCastro, Thanh D Nguyen, Susan A Gauthier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4045663?pdf=render