Perillaldehyde 1,2-epoxide Loaded SLN-Tailored mAb: Production, Physicochemical Characterization and In Vitro Cytotoxicity Profile in MCF-7 Cell Lines

Perillaldehyde 1,2-epoxide Loaded SLN-Tailored mAb: Production, Physicochemical Characterization and In Vitro Cytotoxicity Profile in MCF-7 Cell Lines

We have developed a new cationic solid lipid nanoparticle (SLN) formulation, composed of Compritol ATO 888, poloxamer 188 and cetyltrimethylammonium bromide (CTAB), to load perillaldehyde 1,2-epoxide, and surface-tailored with a monoclonal antibody for site-specific targeting of human epithelial gro...

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Bibliographic Details
Main Authors: Eliana B. Souto, Selma B. Souto, Aleksandra Zielinska, Alessandra Durazzo, Massimo Lucarini, Antonello Santini, Olaf K. Horbańczuk, Atanas G. Atanasov, Conrado Marques, Luciana N. Andrade, Amélia M. Silva, Patricia Severino
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Pharmaceutics
Subjects:
perillaldehyde 1,2-epoxide
compritol ato 888
cationic sln
streptavidin adsorption
mcf-7 cells
Online Access:https://www.mdpi.com/1999-4923/12/2/161

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https://www.mdpi.com/1999-4923/12/2/161

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