Identification of new inhibitors of Mdm2–p53 interaction via pharmacophore and structure-based virtual screening

Identification of new inhibitors of Mdm2–p53 interaction via pharmacophore and structure-based virtual screening

Noor Atatreh,1 Mohammad A Ghattas,1 Sanaa K Bardaweel,2 Sara Al Rawashdeh,1 Mohammad Al Sorkhy1 1Department of Pharmaceutical Sciences, College of Pharmacy, Al Ain University of Science and Technology, Al Ain, Abu Dhabi, United Arab Emirates; 2Department of Pharmaceutical Sciences, School of Pharma...

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Bibliographic Details
Main Authors: Atatreh N, Ghattas MA, Bardaweel SK, Al Rawashdeh S, Al Sorkhy M
Format: Article
Language:English
Published: Dove Medical Press 2018-11-01
Series:Drug Design, Development and Therapy
Subjects:
Protein-protein interaction
virtual screening
Mdm2
p53
anticancer
docking
pharmacophore
ELISA.
Online Access:https://www.dovepress.com/identification-of-new-inhibitors-of-mdm2-p53-interaction-via-pharmacop-peer-reviewed-article-DDDT

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https://www.dovepress.com/identification-of-new-inhibitors-of-mdm2-p53-interaction-via-pharmacop-peer-reviewed-article-DDDT

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