Development of New 1,3-Diazaphenoxazine Derivatives (ThioG-Grasp) to Covalently Capture 8-Thioguanosine

The derivatives of 8-thioguanosine are thought to be included in the signal transduction system related to 8-nitroguanosine. In this study, we attempted to develop new 1,3-diazaphenoxazine (G-clamp) derivatives to covalently capture 8-thioguanosine (thioG-grasp). It was expected that the chlorine at...

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Bibliographic Details
Main Authors: Yasufumi Fuchi, Hideto Obayashi, Shigeki Sasaki
Format: Article
Language:English
Published: MDPI AG 2015-01-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/20/1/1078