Sonic hedgehog improves redifferentiation of dedifferentiated chondrocytes for articular cartilage repair.

Sonic hedgehog (Shh) is involved in the induction of early cartilaginous differentiation of mesenchymal cells in the limb. We investigated whether Shh could promote redifferentiation of dedifferentiated chondrocytes and have a favorable effect on the regeneration of cartilage. Articular chondrocytes...

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Bibliographic Details
Main Authors: Lin Lin, Qi Shen, Tao Xue, Xiaoning Duan, Xin Fu, Changlong Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24533105/?tool=EBI