Molecular Predictors of EGFR-TKI Sensitivity in Advanced Non–small Cell Lung Cancer

<p>The epidermal growth factor receptor (EGFR) is overexpressed in the majority of non-small cell lung cancers (NSCLC) and is a major target for new therapies. Specific EGFR tyrosine kinase inhibitors (TKIs) have been developed and used for the treatment of advanced NSCLC. The clinical respons...

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Bibliographic Details
Main Author: Xiaozhu Zhang, Alex Chang
Format: Article
Language:English
Published: Ivyspring International Publisher 2008-01-01
Series:International Journal of Medical Sciences
Online Access:http://www.medsci.org/v05p0209.htm