Overexpression of EGFR and TGFα in von Hippel–Lindau-Related Central Nervous System Hemangioblastomas

Overexpression of EGFR and TGFα in von Hippel–Lindau-Related Central Nervous System Hemangioblastomas

Background: Central nervous system (CNS) hemangioblastomas (HGBs) are the most frequent cause of mortality in patients with von Hippel–Lindau (VHL) disease. Characteristics of multiple and recurrent disease cause certain difficulties in the treatment of CNS HGBs.Methods: VHL-related HGB cases treate...

Full description

Bibliographic Details
Main Authors: Zhen Liu, Liang Li, Zhiqiang Yi, Hongzhou Duan, Runchun Lu, Chunwei Li, Jingcheng Zhou, Kan Gong
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Oncology
Subjects:
VHL disease
genetic mutation
hemangioblastomas
EGFR
TGFα
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00703/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.00703/full

Similar Items