Origin and Expansion of the Serine Protease Repertoire in the Myelomonocyte Lineage

Origin and Expansion of the Serine Protease Repertoire in the Myelomonocyte Lineage

The deepest evolutionary branches of the trypsin/chymotrypsin family of serine proteases are represented by the digestive enzymes of the gastrointestinal tract and the multi-domain proteases of the blood coagulation and complement system. Similar to the very old digestive system, highly diverse clea...

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Bibliographic Details
Main Authors: Stefanie A. I. Weiss, Salome R. T. Rehm, Natascha C. Perera, Martin L. Biniossek, Oliver Schilling, Dieter E. Jenne
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
serine proteases
trypsin ancestor
complement factor D
proteinase 3
cleavage specificity
Online Access:https://www.mdpi.com/1422-0067/22/4/1658

Internet

https://www.mdpi.com/1422-0067/22/4/1658

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