PKM2 inhibition may reverse therapeutic resistance to transarterial chemoembolization in hepatocellular carcinoma

PKM2 inhibition may reverse therapeutic resistance to transarterial chemoembolization in hepatocellular carcinoma

Abstract Background Therapeutic options for patients with hepatocellular carcinoma (HCC) are limited. Transarterial chemoembolization (TACE) is an interventional procedure used to deliver chemotherapy and embolizing agents directly to the tumor and is the procedure of choice for patients with interm...

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Bibliographic Details
Main Authors: Sean P. Martin, Valerie Fako, Hien Dang, Dana A. Dominguez, Subreen Khatib, Lichun Ma, Haiyang Wang, Wei Zheng, Xin Wei Wang
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Hepatocellular carcinoma
TACE
Therapeutic reprogramming
PKM2
Shikonin
Online Access:http://link.springer.com/article/10.1186/s13046-020-01605-y

Internet

http://link.springer.com/article/10.1186/s13046-020-01605-y

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