Lipoprotein Lipase Inhibitor, Nordihydroguaiaretic Acid, Aggravates Metabolic Phenotypes and Alters HDL Particle Size in the Western Diet-Fed db/db Mice

Lipoprotein Lipase Inhibitor, Nordihydroguaiaretic Acid, Aggravates Metabolic Phenotypes and Alters HDL Particle Size in the Western Diet-Fed db/db Mice

Lipoprotein lipase (LPL) hydrolyzes triglycerides in lipoprotein to supply fatty acids, and its deficiency leads to hypertriglyceridemia, thereby inducing metabolic syndrome (MetSyn). Nordihydroguaiaretic acid (NDGA) has been recently reported to inhibit LPL secretion by endoplasmic reticulum (ER)-G...

Full description

Bibliographic Details
Main Authors: Inhae Kang, Miyoung Park, Soo Jin Yang, Myoungsook Lee
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:International Journal of Molecular Sciences
Subjects:
lipoprotein lipase
nordihydroguaiaretic acid
dyslipidemia
HDL particle size
Online Access:https://www.mdpi.com/1422-0067/20/12/3057

Internet

https://www.mdpi.com/1422-0067/20/12/3057

Similar Items