Paired Expression Analysis of Tumor Cell Surface Antigens

Paired Expression Analysis of Tumor Cell Surface Antigens

Adoptive immunotherapy with antibody-based therapy or with T cells transduced to express chimeric antigen receptors (CARs) is useful to the extent that the cell surface membrane protein being targeted is not expressed on normal tissues. The most successful CAR-based (anti-CD19) or antibody-based the...

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Bibliographic Details
Main Authors: Rimas J. Orentas, Sivasish Sindiri, Christine Duris, Xinyu Wen, Jianbin He, Jun S. Wei, Jason Jarzembowski, Javed Khan
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Oncology
Subjects:
neuroblastoma
gene expression profiling
chimeric antigen receptor-T cells
immunotherapy
GFRA3
GFRA2
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2017.00173/full

Internet

http://journal.frontiersin.org/article/10.3389/fonc.2017.00173/full

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