Extracellular vesicles secreted by Giardia duodenalis regulate host cell innate immunity via TLR2 and NLRP3 inflammasome signaling pathways.

Giardia duodenalis, also known as G. intestinalis or G. lamblia, is the major cause of giardiasis leading to diarrheal disease with 280 million people infections annually worldwide. Extracellular vesicles (EVs) have emerged as a ubiquitous mechanism participating in cells communications. The aim of...

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Bibliographic Details
Main Authors: Panpan Zhao, Lili Cao, Xiaocen Wang, Jingquan Dong, Nan Zhang, Xin Li, Jianhua Li, Xichen Zhang, Pengtao Gong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-04-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0009304