The Molecular and Pathophysiological Functions of Members of the LNX/PDZRN E3 Ubiquitin Ligase Family

The ligand of Numb protein-X (LNX) family, also known as the PDZRN family, is composed of four discrete RING-type E3 ubiquitin ligases (LNX1, LNX2, LNX3, and LNX4), and LNX5 which may not act as an E3 ubiquitin ligase owing to the lack of the RING domain. As the name implies, LNX1 and LNX2 were init...

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Bibliographic Details
Main Authors: Jeongkwan Hong, Minho Won, Hyunju Ro
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Molecules
Subjects:
LNX
UPS
Online Access:https://www.mdpi.com/1420-3049/25/24/5938